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as Brenda Leigh Johnson
as Earl Sinclair (voice)
as Lindsay Weir
as Vincent Martino / Frankie Martino
as Jake Epping
as Blue
as Spider-Man / Peter Parker
as Caesar
as Oz
as Aron Ralston
as Himself
as Ned Fleming
as Dave Skylark
as Mac McLeod
as Buster Scruggs (segment "The Ballad of Buster Scruggs")
as Elizabeth Gilbert
as Dale Denton
as Tom Reed
as Tommy Wiseau
as Alien
as Tristan
as Himself (archive footage)
as Ed Mass
as Lemmy (voice)
as Thadeous
as Jake Huard
as Janet Harrison
as Elmo / Pestie / Grouch Jailer / Grouch Cab Driver (voice)
