as Wade Wilson / Deadpool / Nicepool

as Rob McGregor

as Nicolas 'Nick' Bannister

as Logan / X-24

as Charlie Kenton

as Sir Lionel Frost (voice)

as Logan / Wolverine

as Chappie

as P. T. Barnum

as Keller Dover

as Van Helsing

as Alfred Borden

as Davis (segment "The Catch")

as Peter Pan

as Frank Tassone

as Lady Sarah Ashley

as Sid Waterman

as Jane Goodale

as Eddie "the Eagle" Edwards

as Wyatt Bose

as Kate McKay

as Gabriel Shear

as Tomás/Tom Creo/Tommy

as Aleksey Andreev

as Boyd Bolton

as Logan / Wolverine

as Bill

as Cass

as Jack 'Spot' Comer

as Logan / Wolverine / Weapon X